Helen Lee, M.D. President/CEO

Hyun Jung Helen Lee, MD, MHCM is a Gynecologist by training and has been working on the development of anti-cancer drugs for 15 years in Global, the US and the Asia. Prior to joining Samyang, she served as the Global Head of Solid Tumor Clinical Development at Shire in the US. She has held various executive positions at Baxalta, Eli Lilly and Pfizer. After graduating from Yonsei University College of Medicine, she completed her residency training at Severance Hospital, and later, earned her master’s degree in Health Care Management at Harvard School of Public Health. Since 2016, She has served as Chief Strategy Officer (CSO) and Chief Medical Officer (CMO) at Samyang. The company named Hyun Jung Helen Lee as President of Samyang Biopharm USA in 2018 to lead Samyang’s effort in developing a drug pipeline comprised of drugs to treat select cancers and rare diseases.

Sean D. McKenna, Ph.D. VP, Research

Sean McKenna received his Bachelor’s degree in biology at University of Massachusetts at Amherst, Ph.D. in biomedical science at University of Connecticut School of Medicine. Following his postdoctoral training at the Jackson Laboratory, Dr. McKenna worked for over twenty years at Serono and EMD Serono in roles of increasing responsibility, culminating as Senior Director of Protein Engineering and Antibody Technologies, where he was responsible for all biotherapeutic discovery activities within the US subsidiary. Highlights within his career include co-inventorship of the first effector-competent anti-PD-L1 antibody, Bavencio, currently approved in Merkel cell carcinoma and metastatic bladder carcinoma, as well as the development of M7824, a novel clinical stage bispecific PD-L1 and TGF-beta antagonist. Mr. McKenna joined Samyang Biopharm USA as the Vice President of Research in October 2018.

Barbara Natke, Ph.D., MBA Acting VP, Bus. Development

Barbara Natke received her Bachelor’s degree in Biology from Loyola University of Chicago and her Ph.D in Biochemistry from Boston University School of Medicine. Following postdoctoral training in the Department of Biological Engineering at the Massachusetts Institute of Technology, Barbara embarked on a twenty-year career of increasing responsibilities at various Biotech/Pharma companies including Genzyme/Sanofi and Shire/Takeda. There she supported nonclinical and clinical development of key corporate assets including Campath/Lemtrada, Myozyme/Lumizyme, and Elaprase. During her career, Barbara migrated to the business side of the industry to drive corporate strategy through asset evaluation, in-licensing and portfolio management and received her MBA from the F.W Olin Graduate School of Business at Babson College. Dr. Natke joined Samyang Biopharm USA in 2019 as a Senior Director of Business Development and assumed the role of Acting VP of Business Development in 2021.

Scientific Advisory Board

Louis M. Weiner

Professor and Chairman
Department of Oncology Georgetown University Medical Center

Lombardi Comprehensive Cancer Center Georgetown University Medical Center

Lawrence Fong

Professor and Leader
Department of Oncology Cancer Immunotherapy Program

Helen Diller Family Comprehensive Cancer Center
University of California, San Francisco

Thomas F. Gajewski

AbbVie Foundation Professor
Cancer Immunotherapy, Departments of Pathology, Medicine and the Ben May Department for Cancer Research

University of Chicago